Analytical Chemistry (Ⅰ)

Course Code:B32011Y

Course Name:  Analytical Chemistry ()

Credits: 2.0

Level: Undergraduate

Pre-requisite: Chemical Principle

Lecture Time: 40 class hours


Course Description

"Analytical Chemistry I" is the first part of "Analytical Chemistry". "Analytical Chemistry" is one of the main courses in chemistry that involves many disciplines and majors.This course is mainly about the basic knowledge of analytical chemistry, chemical analysis and data processing knowledge, which is divided into three major parts.The purposes of teaching areTo make students understand the thinking methods, connotation and extension of analytical chemistry, the characteristics and uses of this subject. Learning important methods and uses to study the composition of material,content, the relationships between structure and function at the molecular level, which cover analytical chemistry ideas, strategies of method development and quantitative analyses. To grasp the basic principles of analytical chemistry, important concepts and some basic analysis methods and techniques firmly, so that it becomes a kind of ability and wisdom to solve problems. In the teaching process, students can understand the vertical and horizontal theoretical basis and their relationships in analytical chemistry, through the introduction and study of the source knowledge, adjacent subject knowledge, analytical chemistry and its professional knowledge. To increase students' interest in the knowledge of various subjects that have been mastered and about to be learned, promoting the students' awareness of relevant theories, knowledge and technology. Focusing on basic theories, basic concepts, classical methods of quantitative analytical chemistry to help students develop an analytical chemistry concept of rigorous thinking and strict style. Extending teaching is also necessary, which covers some knowledge and progress of analytical chemistry research, especially for the forefront, the latest developments and achievements of analytical chemistry research, broadening students’ horizons. Teaching students the ideas and strategies in analytical chemistry to analyze and solve problems, helping them establish a dynamic analysis of analytical chemistry thinking mode, laying a solid foundation for further study.

Topics and Schedule

  1. Basis of Analytical Chemistry (12 hrs)
    1. Introduction (2 hrs)

    1.1. Definition, classification, task and function of analytical chemistry

    1.2. Development history and trend of analytical chemistry

    1.3. Knowledge base and learning points

  1. Theoretical basis and data processing of Analytical Chemistry (6 hrs)

    2.1. Composition of analytical chemistry theory

    2.2. Construction points of analytical methods

    2.3. Development, selection and optimization of analytical methods

    2.4. Errors in Analytical Chemistry

    2.5. Effective number and its operation rules

    2.6. Data processing in Analytical Chemistry

    2.7. Significance test

    2.8. Rejecting data

    2.9. Regression analysis method

    2.10. Accuracy and precision of analytical results

    2.11. Method reliability test

  1. Collection and preparation of samples (2 hrs)

    3.1. Collection, preparation and decomposition of samples

    3.2. Pretreatment before determination

  1. Quality control and safeguard measures2 hrs

    4.1. Job content of quality control and safeguard

    4.2. Standard methods and materials

    4.3. Uncertainty and traceability

    4.4. Metrology accreditation and qualification examination in the laboratory

  1. Chemical analysis (24 hrs)
  2. Basis of chemical analysis4 hrs

    1.1. Principle of titration analysis

    1.2. Types and structure points of titration method

    1.3. Determination and indication of end point of titration

    1.4. Titration standard solution and solution preparation of samples

    1.5. Calculation data and error analysis

  1. Acid-base titration method6 hrs

    2.1. Principle of acid base titration and stoichiometry of neutralization reaction

    2.2. Type, terminal and acid-base indicator of titration

    2.3. Data and error analysis

    2.4. Application of acid-base titration method

    2.5. Brief introduction of acid-base titration in non aqueous solvent

  1. Coordination reaction titration method4 hrs

    3.1. Basic principle of coordination reaction titration method

    3.2. Coefficient of side reaction and condition stability constant

    3.3. Condition of quantitative titration

    3.4. Data analysis

    3.5. Titration methods and applications

  1. Oxidation reduction titration method

    4.1. Principle and method of oxidation reduction titration

    4.2. Analysis of data

    4.3. Classical titration method and its application

  1. Precipitation titration method2 hrs

       5.1. The principle, method and characteristics of precipitation titration

5.2. Some classical methods such as argentometry, Mohr method, Volhard    method, Fajans method etc.

       5.3. Preparation and calibration of standard solution of precipitation

  1. Gravimetric analysis2 hrs

       6.1. The basic principle of gravimetric analysis

       6.2. Solubility of precipitation and its influencing factors

       6.3. The type and formation of precipitation

       6.4. The main factors what affecting the purity of precipitation

       6.5. Choice and control of precipitation conditions

       6.6. Classification and application of organic precipitator

       6.7. Weighing and result calculation

  1. Absorption spectrophotometry2 hrs

       7.1. The basic law of substance to light absorption

       7.2. Absorption spectrum and display reaction

       7.3. Spectrophotometer and absorption spectrophotometric analysis

       7.4. Other absorption spectrophotometry

       7.5. Applications of absorption spectrophotometry


Wuhan University, Analytical Chemistry I, Fifth Edition, Higher Education Press, 2006 (reprinted in Dec.2014)


[1]     Kean Li, Analytical Chemistry Course, Peking University Press, Beijing,2005

[2]     Donald M. West, F. James Holler, Stanley R. Crouch Douglas and A. Skoog, Fundamentals of Analytical Chemistry, 9th Edition [International Edition],2013

[3]     D.A. Skoog, D. M. West, F. J. Holler, and S. R. Crouch, Analytical Chemistry, 7th Edition, Saunders College Publishing,1999

[4]     RKellner, Analytical Chemistry, Translated by Qinhan Jin and Kean Li etc., Peking University Press, 2001

[5]     Erkang Wang, Analytical chemistry in Twenty-first Century, Science Press